Skip to main content
Fig. 2 | Genome Biology

Fig. 2

From: ExOrthist: a tool to infer exon orthologies at any evolutionary distance

Fig. 2

Calibration of ExOrthist’s conservation cut-offs. Estimation of default conservation cut-offs for each evolutionary distance range from two-species ExOrthist runs. The selected default conservation cut-offs are highlighted by a vertical dashed line. a,d Human and mouse (short evolutionary distance range). b,e Human and zebrafish (medium evolutionary distance range). c,f Human and fruitfly (long evolutionary distance range). a–c The line charts depict the number of exons from each species included in ExOrthist orthogroups (OGs) when different sequence similarity cut-offs are set [0.1–0.9]. The barplots on top represent the number of exon orthogroups retrieved by ExOrthist with the corresponding sequence similarity cut-off. All ExOrthist runs were performed with a fixed exon length ratio (shortest/longest) cut-off of 0.40. d–f The line charts depict the number of exons for each species included in ExOrthist orthogroups when different exon length ratio (shortest/longest) cut-offs are set [0.4–0.9]. The barplots on top represent the number of exon orthogroups retrieved by ExOrthist with the corresponding exon length ratio cut-off. ExOrthist runs were performed with the previously identified default sequence similarity cut-off (d 0.5, e 0.3, f 0.1). See “Methods” for details on the other settings for each run

Back to article page