Fig. 1
From: MAAPER: model-based analysis of alternative polyadenylation using 3′ end-linked reads
Overview of the MAAPER method. A A schematic illustrating the generation of nearSite reads (e.g., QuantSeq FWD, 10x Genomics) and onSite reads (e.g., QuantSeq REV). B Outline of the MAAPER method. MAAPER takes aligned nearSite reads and a PAS database (polyA_DB) and outputs predicted PAS positions and APA analysis results. Two APA metrics are generated, namely, relative expression difference (RED) and relative lengthen difference (RLD)