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Table 1 Runtime and memory consumption of Haploflow, SAVAGE in de novo mode (version 0.4.1), metaSPAdes (3.14), and MEGAHIT (1.2.9). Time and memory is averaged for the HCMV mixtures. SAVAGE did not successfully complete on the HCMV in vitro mixtures and the simulated virome data. Values were calculated using Linux’ time command

From: Haploflow: strain-resolved de novo assembly of viral genomes

Software/data set

HIV 3 in silico mixture

 

HCMV in vitro mixture

 

Simulated virome

 

Metric

CPU user time (seconds)

Memory peak (GB)

Avg. CPU user time (seconds)

Avg. memory peak (GB)

CPU user time (seconds)

Memory peak (GB)

Haploflow

724

0.009

5170

17.509

18,245

47.678

SAVAGE

110,208

102.938

75,518

17.658

–

–

PEHaplo

10,127

11.819

58,920

13.998

–

–

metaSPAdes

1500

1.054

42,906

65.641

25,996

23.399

MEGAHIT

250

0.269

2910

0.754

9,690

2.148