Skip to main content
Fig. 3 | Genome Biology

Fig. 3

From: Dissecting indirect genetic effects from peers in laboratory mice

Fig. 3

Superimposed Manhattan plots corresponding to igeGWAS (top panel) and dgeGWAS (bottom panel) of the same 170 phenotypes. DGE associations with a negative log P value greater than 10 were truncated at this threshold (as indicated by 10+); also, data points with negative log P values smaller than 2 are not shown. The larger dots correspond to the most significant variant at each significant IGE or DGE locus (FDR < 10%). In the IGE panel (top), each color corresponds to a class of phenotypes: behavioral (red, includes seven behavioral phenotypes with a significant IGE locus), adult neurogenesis (black, two phenotypes with a significant IGE locus), immune (orange, one phenotype with a significant IGE locus), hematological (yellow, one phenotype with a significant IGE locus), blood biochemistry (blue, two phenotypes with a significant IGE locus), bone phenotypes (green, two phenotypes with a significant IGE locus), heart function (brown, one phenotype with a significant IGE locus), and lung function (purple, one phenotype with a significant IGE locus). In the DGE panel (bottom), the same coloring scheme is used as in the IGE panel except for gray dots, which are for phenotypes that do not have any significant IGE locus

Back to article page