Fig. 3
From: Coordinated changes in gene expression kinetics underlie both mouse and human erythroid maturation
A set of genes with complex expression kinetics confounds velocity estimation in erythropoiesis. A Illustration of phase plot representation in datasets of differentiating cell populations, and associated scVelo predictions. B Illustration of strategy for MURK gene identification. C Phase plots of representative MURK genes. x-axis: normalized imputed counts of spliced transcript; y-axis: normalized imputed counts of unspliced transcript. D GO-term enrichment of MURK genes identified in mouse yolk sac erythropoiesis. E Zoomed-in UMAP of the erythroid branch (see Fig. 1 for full UMAP) with scVelo calculations, before and after removing MURK genes identified in B. Distinct waves of embryonic erythropoiesis are visible upon MURK gene removal, highlighted with arrowheads