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Fig. 4 | Genome Biology

Fig. 4

From: Optimizing expression quantitative trait locus mapping workflows for single-cell studies

Fig. 4

Comparison between covariate adjustment approaches. a Number of eGenes obtained when using different approaches to account for covariates, as a function of the number of factors used as covariates (out of 20,545 genes tested). b Number of replicated discoveries using a-bulk (all samples, n = 526). Replication defined as FDR < 10% and consistent direction of effect. The optimal number of covariates for each method is highlighted with an open circle

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