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Fig. 1 | Genome Biology

Fig. 1

From: LIQA: long-read isoform quantification and analysis

Fig. 1

Framework of LIQA. A The flowchart to illustrate how LIQA works. The inputs to LIQA are long-read RNA-seq data and isoform annotation file. LIQA models observed splicing information, high error rate of data, and read length bias. The output of LIQA are isoform expression estimates and detected DAS events. B Quantification of potential 3′ bias of long-read RNA-seq data. Complete (orange) and truncated (blue) long reads are jointly modeled to correct read length bias by estimating read length distribution

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