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Table 2 Disentanglement metrics for two splatter-simulated single-cell RNA-seq datasets with four ground truth variables

From: MichiGAN: sampling from disentangled representations of single-cell data using generative adversarial networks

  

Spearman correlation gap ↑

FactorVAE metric ↑

MIG ↑

Linear step

PCA

0.57

0.36

0.56

 

VAE

0.37

0.44

0.39

 

β-TCVAE

0.65

0.33

0.72

Non-linear step

PCA

0.60

0.36

0.58

 

VAE

0.4

0.38

0.38

 

β-TCVAE

0.55

0.34

0.73

  1. The dimensionality of the latent space was 4 for all three approaches