Fig. 6

Comparing molecules (scSNV collapse) or tags (scSNV tags) with at least five co-expressed SNVs. For each sample, we identified the unique sets of SNVs detected by at least one molecule/read and we counted the number of germline SNVs, A>G edits, and unknown changes. For each set where the count of the maximal SNV type was more than half the total count, we assigned it as having a dominant SNV type. We then merged all of the sample sets together without removing duplicate entries. We calculated values for SNV data from scSNV (a, c, e) and Cell Ranger (b, d, f) and plotted 2D-histograms of dominant SNV type count versus the total number of SNVs in the molecule for SNVs overlapping germline (if available) and 1000 Genomes calls (a, b), A>G edits (c, d), and unknown SNVs (e, f). The log counts for each 2D bin are indicated by the color bars beside each heatmap