Fig. 5

Significant associations identified by MARS and the univariate test in NFBC data. a Number of significant associations identified by MARS and the univariate test. The x-axis shows the 10 traits of NFBC data and the y-axis shows the number of set-based associations that will likely be associated with the traits. The blue bars show associations identified by MARS and the orange bars show associations identified in the univariate test. The 10 phenotypes are triglycerides (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), glucose (GLU), insulin (INS), body mass index (BMI), C-reactive protein (CRP) as a measure of inflammation, systolic blood pressure (SBP), diastolic blood pressure (DBP), and height. b A Venn diagram showing the number of loci was found by the GWAS catalog for 10 traits. The red circle shows the number of loci identified by MARS, the blue circle shows the number of loci identified by the univariate test, and the green circle shows the number of identifications reported by the GWAS catalog