Fig. 5
From: Intergenic RNA mainly derives from nascent transcripts of known genes
Impact of nuclease depletion on TU expression. a Expression levels of protein-coding genes and TUs in the chromatin and nucleoplasm fractions. b Relative nucleoplasmic-to-chromatin expression levels in response to EXOSC3 knockdown and control siLuc treatments. c Expression levels in CSTF2+CSTF2T and CPSF3 knockdowns relative to control in the chromatin fraction. d Expression levels in XRN2 knockdown (via activation of the auxin-inducible degron system) and basal (uninduced; minus auxin) treatments relative to unmodified XRN2 control in the nuclear fraction. p values were calculated using the two-sided Wilcoxon rank sum test, with asterisks indicating statistical significance at the following thresholds: nsp > 0.05; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001