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Fig. 5 | Genome Biology

Fig. 5

From: PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity

Fig. 5

Effects of PD-L1-lnc on the growth of lung cancer xenografts in mice. a Change in body weight throughout the experiment. b Change in tumor volume. c The size and weight of various tumors 30 days post-engraftment. Scale bar, 1 cm. d Proliferation of implanted tumors. Upper: representative immunohistochemical staining of Ki67 in implanted tumors; Lower: quantitative analysis. Scale bar, 100 μm. e RT-PCR analysis of the expression levels of PD-L1-lnc in the implanted tumors. Upper: gel image of PCR product; Lower: RT-PCR analysis. NS, no significance; *P < 0.05; **P < 0.01; ****P < 0.0001

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