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Fig. 2 | Genome Biology

Fig. 2

From: Determination of complete chromosomal haplotypes by bulk DNA sequencing

Fig. 2

Statistical metrics of molecular haplotype linkage between variants at different genomic distance extracted from linked-reads and Hi-C sequencing data of RPE-1 (a,c,e) and NA12878 (b,d,f) cells. a, b Fraction of linked variants. c, d Average number of links between linked variants. e, f Fraction of links consistent with cis linkage. The residual linkage in the linked-reads data 50% accuracy (e and f) reflects tagging of unrelated DNA fragments from both parental homologs by the same molecular barcodes by chance

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