Fig. 1

Third-generation sequencing technologies and their characteristics (read length, error rate and scale of information). The read length and scale of information (local versus chromosome-scale) together determine the haplotype range that can be achieved; moving down the schematic this range increases (orange arrow). Sequencing costs per sample increase moving from short-read sequencing down to nanopore sequencing, and then decrease again for BioNano and Hi-C (yellow arrows). Similarly, read length and error rate first increase moving down to nanopore sequencing, and then decrease again for BioNano and Hi-C (green arrows)