Fig. 3
From: MEDALT: single-cell copy number lineage tracing enabling gene discovery
Convergent evolution in TNBCs. a Genes associated with convergent evolution in the 20 TNBC patients. Labeled at the top are known cancer genes. AMP, copy number amplification; DEL, copy number deletions; MIX, genes with amplifications and deletions. b The gene knockoff effect scores of gene set identified from the MEDALTs and the MP trees by PLSA (p value < 0.001). Included as controls are 100 sets of 107 randomly selected genes, 234 oncogenes and 269 tumor suppressors (TS) in oncoKB and intOGen. c The MEDALT of patient KTN102. Orange boxes highlight lineages under potential convergent evolution. d Progression-free survival of breast cancer patients with and without FAAP24 loss in TCGA