Skip to main content

Table 2 Summary of approaches that address sources of uncertainty in environment specification. Highlighted in bold are key approaches related to probabilistic or ensemble-based methods

From: Addressing uncertainty in genome-scale metabolic model reconstruction and analysis

Approach

Sources of uncertainty

References

Media databases

Inconsistent media definition

[62, 63]

Experimental determination

Undefined environment composition

[64,65,66,67,68]

Phenotype phase plane

Variable environment composition

[71, 72]

Ensemble sampling

Variable environment composition

[73,74,75,76,77,78,79]

Probabilistic sampling

Variable environment composition

[80]

Reverse ecology

Undefined environment composition

[81,82,83,84,85]