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Fig. 1 | Genome Biology

Fig. 1

From: Addressing uncertainty in genome-scale metabolic model reconstruction and analysis

Fig. 1

A general progression for genome-scale metabolic model reconstruction and analysis is represented by five major steps. The central black arrows demonstrate a standard approach, which yields a single output from each step. The gray arrows represent the uncertainty in this process, with the output of each step as an ensemble of possible results. The new additions to the model at each step are shown in red: circles represent metabolites, stars represent biomass components, arrows represent metabolic reactions, and bold arrows represent a specific flux distribution

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