Fig. 5

Scatterplot of TGF-alpha and disease-associated CTP-scores, real white blood cell counts, CRP-MPS, MOA-MPS, and MOMENT-MPS in the Lothian Birth Cohort 1936 (N = 823). Scatterplots and marginal histograms of TGF-alpha (rank-based inverse transform) vs disease-associated CTP-scores (dark red), real white blood cell counts (109/L, in orange), DNA methylation-derived CRP-scores (gray), MOA- (dark green), and MOMENT-MPS of meta-analyses of three neurodegenerative disorders (dark blue), which included amyotrophic lateral sclerosis, Alzheimer’s disease, and Parkinson’s disease. The red line shows the best linear fit to the data, with gray background representing the s.e.