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Table 1 My Personal Mutanome database statistics

From: My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

Entities

 Protein

21,759

 

 Mutation

490,245

 

Interface

72,953

Non-interface

417,292

 Mutation case

544,692

 

Interface

85,484

Non-interface

459,208

 PPI

121,172 from 3 sources:

 

PDB

4112

Interactome3D

2891

ECLAIR

114,169

 Functional site

535,182 in 8 types:

 

Acetylation

43,764

Malonylation

4476

Methylation

14,649

O-linked glycosylation

4228

Phosphorylation

276,738

Succinylation

1665

Ubiquitination

100,246

Ligand binding

89,416

 TCGA

11,315 cases in 33 cancer types

 

 Drug

251

 

 PDB

41,843

 

95,599 PDB chains for 6583 proteins

 

20,132 PDBs for 9589 PPI

 

5126 PDBs for 6482 PPI (hetero)

 

17,595 PDBs for 3107 PPI (homo)

 

Relations

 

PPI (edgetic)

Protein functional site (nodetic)

 Mutation

775,524 mapped interface mutations

450,685 mapped mutations

 Cancer

7285 survival analyses

2,087,382 oncoPPI tests

1599 survival analyses

 Drug

252,275 drug responses

1,018,857 drug responses

  1. PPI protein-protein interaction, Hetero PPI PPI consisting of different proteins, Homo PPI PPI of the same protein