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Fig. 8 | Genome Biology

Fig. 8

From: ReSeq simulates realistic Illumina high-throughput sequencing data

Fig. 8

Comparison between bwa and bowtie2 on E. coli. Each dataset has simulations trained on mappings from bwa and bowtie2. ac Statistics of mapping outcomes. Bowtie2 does not clip and therefore has no soft-clipped bases. df Mapping quality distribution. Mapping qualities are cumulative, i.e., all mapping qualities at the given score or higher. Markers are only shown for mapping qualities 0,2,30,42 for bowtie and 0,1,30,60 for bwa. gi Mapping accuracy for all mapping quality thresholds. Markers are only shown for mapping qualities 0,2,30,42 for bowtie and 0,1,30,60 for bwa. Positives are mapped reads, which fulfill the correctness criteria (TP) or do not (FP). Overlapping: True and mapped positions overlap independent of strand. Correct_start: Perfect match of start position and strand. Correct: Perfect match of start and end positions and strand. a, d, g Ec-Hi2000-TruSeq. b, e, h Ec-Hi2500-TruSeq. c, f, i Ec-Hi4000-Nextera

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