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Fig. 4 | Genome Biology

Fig. 4

From: Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes

Fig. 4

Partial correlation analysis results of the autoimmunity predictive signature evaluated at different timeframes before seroconversion. a 12–9 MBSC. b 9–6 MBSC. c 6–3 MBSC. d 3–0 MBSC. Genes, metabolites, and vitamins are represented as circles, triangles, and squares, respectively. Node color indicates mean up- (red) or down- (blue) regulation of the feature in cases at the first network time point. Edges’ color indicates positive (blue) or negative (red) correlation. Only links with absolute partial correlation values > 0.7 are represented

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