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Table 1 Genes with GReX found in association with breast cancer-specific survival in AA women

From: A framework for transcriptome-wide association studies in breast cancer in diverse study populations

RegionGeneHazard ratio (90% CI)aZ-statisticaP valueaGReX R2 (h2)b
20q13.2AURKA0.83 (0.73, 0.95)−2.521.5 × 10−30.021 (0.055)
2p23.1CAPN131.22 (1.07, 1.41)2.765.4 × 10−40.011 (0.047)
3q26.32PIK3CA0.85 (0.74, 0.97)−2.343.2 × 10−30.020 (0.033)
18q21.33SERPINB50.82 (0.72, 0.93)−2.853.4 × 10−40.010 (0.026)
  1. aHazard ratio and FDR-adjusted 90% confidence intervals, Z-statistic, and P value of association of GReX with breast cancer-specific survival
  2. bCross-validation R2 of gene expression in AA models