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Fig. 2 | Genome Biology

Fig. 2

From: A framework for transcriptome-wide association studies in breast cancer in diverse study populations

Fig. 2

Predictive performance of models in cross-validation, external validation, and across race. a Comparison of cross-validation R2 across race in CBCS. Cross-validation R2 in CBCS WW women (X-axis) and CBCS AA women (Y-axis) for each of the 151 analyzed genes. Scales are logarithmic. Dotted lines represent R2 = 0.01. Colors represent the model with which a given gene can be predicted at R2 > 0.01. b Comparison of validation R2 across race in TCGA for 149 analyzed genes found in TCGA expression data. c Comparison of validation R2 across race in held-out CBCS samples for 50 analyzed genes. d Comparison of R2 of genes in TCGA AA sample imputed from WW models (X-axis) and the AA models (Y-axis). e Comparison of R2 of genes in held-out CBCS AA sample imputed from WW models (X-axis) and the AA models (Y-axis)

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