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Fig. 1 | Genome Biology

Fig. 1

From: A framework for transcriptome-wide association studies in breast cancer in diverse study populations

Fig. 1

CBCS eQTL results across race and compared with GTEx. a Cis-trans plot of top eQTL by gene stratified by self-reported race. Each point represents the top eQTL for a given gene. The color and size of each point reflects the Benjamini-Bogomolov FDR-adjusted P value (BBFDR) for that eQTL. eGenes with BBFDR < 0.01 are labeled. b Comparison of effect sizes of eGenes with significant cis-eQTLs in CBCS (Y-axis) and GTEx (X-axis) over tissue type, stratified by race. eGenes are colored by the GTEx tissue that shows the largest effect size. GTEx effect sizes on the X-axis are multiplied by the sign of the correlation between the genotypes of the GTEx and CBCS eSNPs

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