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Fig. 4 | Genome Biology

Fig. 4

From: Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana

Fig. 4

Clustering analysis of cMHSs and sMHSs. a Heatmaps of cMHSs and sMHSs generated by k-means cluster analysis using epigenetic marks H3K27ac, H2A.Z, H3K27me3, and CG DNA methylation. Genomic regions up- and downstream 1 kb of centers of MHSs were divided into 40 bins. The average read depth in each bin was calculated. The average read depth from each data set was then scaled from 0 to 1 and plotted as a heatmap. The five classes identified by k-mean cluster analysis are marked by black lines. b Percentage of cMHSs and sMHSs within each of the five classes

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