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Fig. 4 | Genome Biology

Fig. 4

From: Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

Fig. 4

Identifying and validating predicted causal genes. a Schematic representation of association and colocalization approaches. b Schematic representation of extrapolating the dose-response curve to the Mendelian end of phenotypic variation spectrum [37]. c Proportion of GWAS-associated loci per trait that contain colocalized and PrediXcan-associated signals for expression and splicing

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