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Table 1 Peptide sequences derived from isoforms detected by proteome analysis

From: Aberrant splicing isoforms detected by full-length transcriptome sequencing as transcripts of potential neoantigens in non-small cell lung cancer

Detected peptide

Peptide-detected cell lines (proteome analysis)

Isoform-detected cell lines (MinION)

Gene symbol

Type

GENCODE

NLPSNPLEFNPDVLK

H1650, II-18, RERF-LC-KJ

A427, ABC-1, H1437, H1648, H1650, H1819, H2126, H2228, H2347, II-18, PC-9, RERF-LC-KJ, VMRC-LCD

ESYT2

Unannotated exon

ENST00000275418

NLPSNPLEFNPDVLKK

H1650, II-18, PC-9

A427, ABC-1, H1437, H1648, H1650, H1819, H2126, H2228, H2347, II-18, PC-9, RERF-LC-KJ, VMRC-LCD

ESYT2

Unannotated exon

ENST00000275418

TLGEIDAQHIQGVQETATDPR

H1650

H1650, H2228, H2347, II-18, RERF-LC-OK

FAM126A

Unannotated exon

ENST00000409923

DRLEEGCLK

RERF-LC-Ad1

H1437, H2126, II-18, RERF-LC-Ad1

KRT7

Alternative 5′ splice site

novel

EVPMVVVPPVGAK

A549, H2228

A549, H1437, H1819, H2228, H322

RRBP1

Alternative last exon

ENST00000398782

HLDAHTAAHSQSPR

RERF-LC-Ad2

H322, RERF-LC-Ad2

SUN1

Combination (shuffling, unannotated exon)

Novel

RHLDAHTAAHSQSPR

RERF-LC-Ad2

H322, RERF-LC-Ad2

SUN1

Combination (shuffling, unannotated exon)

Novel