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Fig. 4 | Genome Biology

Fig. 4

From: Compacting a synthetic yeast chromosome arm

Fig. 4

Stepwise chromosome compaction by iterative SGC. a Stepwise chromosome compaction by three rounds of iterative SGC. The LU profiles of selected 5-FOA resistant strains after SGC are shown using the strategy as detailed in Fig. 2a. The newly deleted LUs in each round of SGC are indicated by asterisks. b The number of LUs deleted in strains in a. ZLY298 is identified after the first round of SCRaMbLE. ZLY348 is from the second round of SGC and ZLY349 is from the third round of SGC. c The lengths of deleted synthetic sequence in strains in a. d The numbers of deleted genes in strains in a

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