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Fig. 2 | Genome Biology

Fig. 2

From: Comprehensive integrative profiling of upper tract urothelial carcinomas

Fig. 2

Distribution of mutations affecting ZFP36 family genes in UTUC and several public bladder carcinoma datasets. Lollipops represent mutations of a ZFP36L1, b ZFP36L2, and c ZFP36 genes. d Distribution of mutation frequency of ZFP36L1 in different public bladder carcinoma cohorts using the cBioPortal database. e Distribution of mutation frequency of ZFP36 family in different bladder carcinoma cohorts using the cBioPortal database. f Box plot representing the mutational load in UTUC samples according to ZFP36 family gene mutations. g Box plot representing mutational load in bladder carcinoma TCGA cohort according to ZFP36 family mutations. h Kaplan-Meier curves for overall survival of patients with bladder carcinomas in TCGA cohort according to ZFP36 family gene mutations status. i Kaplan-Meier curves for progression-free survival of patients with bladder carcinomas in TCGA cohort according to ZFP36 family mutations

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