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Fig. 4 | Genome Biology

Fig. 4

From: Homology-mediated inter-chromosomal interactions in hexaploid wheat lead to specific subgenome territories following polyploidization and introgression

Fig. 4

Properties of TAD-like domains in AK58 seedlings. a Normalized contact map for chromosome 1A (1-Mb bins). b Hi-C contact map for the enlarged region of chromosome 1A (10-kb bins). c Cumulative fraction of TAD-like domain sizes in AK58. The x-axis presents the TAD length, whereas the y-axis presents the fraction of TADs that are shorter than a given length on the x-axis. d Density of high-confidence gene models surrounding TAD-like domain boundaries. The y-axis presents the number of genes per kb. The shaded area indicates the TAD-like domain. Randomly assigned TAD-like domains in genomes were used as the background (blue line). e Distributions of gene expression density at the TAD-like domain boundaries, inside the TAD-like domains, and in regions lacking TAD-like domain structures. f Sequence motifs enriched at TAD-like domain boundaries. The densities of sequence motifs surrounding TAD-like domain boundaries (per kb) are plotted. Top to bottom: motifs enriched in bread wheat TAD-like domain boundaries (first two panels), TCP motif enriched in rice TAD-like domain boundaries, and the CTCF-binding sequence enriched in human TAD-like domain boundaries. The enrichment statistics are summarized in Additional file 1:Supplemental TableĀ 5

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