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Fig. 1 | Genome Biology

Fig. 1

From: STARRPeaker: uniform processing and accurate identification of STARR-seq active regions

Fig. 1

Comparison of STARR-seq output coverage calculated using the center of the fragment to using the start position of the sequencing read. a Distribution of the shift in final peak locations resulting from using two alternative coverage counting schemes in HepG2. Comparison of b overall fold enrichment level, c P value, and d size of resulting peaks. e Example highlighting the difference between fragment-based and read-based coverage counting schemes and their resulting peak calls from HepG2 STARR-seq data. Asterisks represents statistical significance using the Mann-Whitney-Wilcoxon test two-sided with Bonferroni correction; *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001

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