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Fig. 3 | Genome Biology

Fig. 3

From: Tissue-specific usage of transposable element-derived promoters in mouse development

Fig. 3

Dynamic accessibility changes of TEs during mouse embryonic development. a Percentage of dynamically changed accessible TEs at two development stages in five mouse tissues. E14.5d: the accessible TEs with higher accessibility in the E14.5 development stage; P0d: accessible TEs with higher accessibility in P0day; E14.5&P0d mean accessible TEs did not significantly change their accessibility between the two stages. b Expression pattern of genes around accessible TEs at two development stages in five mouse tissues (Wilcoxon signed-rank test). c Percentage of dynamically changed accessible TE-derived TSS at two development stages in five mouse tissues. d Epigenome browser view of ATAC-seq signals around the dynamically changed accessible TE-derived TSS of protein-coding genes (left three) and lincRNA (right one). e Tissue- and developmental stage-specific enrichment of predicted transcription factors binding motifs in dynamically changed accessible TEs at E14.5 (left) and P0 (right) in five mouse tissues. The color of the dot indicated the enrichment p-value of motif; the size represented the percentage of DARs that contained the TF motif. f Developmental stage-specific expression pattern of TFs that predicted to bind the dynamically changed accessible TEs at E14.5 (top) and P0 (bottom) in five mouse tissues. The dashed line indicated no expression difference of TFs between two stages. N.A: no TF motif was enriched in stomach P0d DARs

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