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Fig. 5 | Genome Biology

Fig. 5

From: AlphaBeta: computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants

Fig. 5

Analysis of CG epimutations in apomictic dandelion. a Using single-seed descent from a single apomictic triploid founder genotype, 8 replicated lineages were propagated for 6 generations. DNA methylation measurements were obtained using epigenotyping by sequencing (epiGBS). b Overview of the data: N is the total number of sequenced samples; Seq depth is the average sequence depths of the samples; # TP is the number of unique time-points that are sampled; max. Δt is the maximum divergence time (in generations) between samples. *Note: the calculation of average read coverage was based only on interrogated cytosines as epiGBS does not yield any genome-wide data. c Model fits to the CG divergence data. Highly significant increases in 5mC divergence (D) over generation time (Δt) were detected in all sequence contexts, despite the relatively large variation in 5mC divergence patterns (see text)

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