Fig. 2

Identification of doublet cells. a Receiver operating characteristic (ROC) curves of the tested doublet detection methods for three datasets with SNP-identified doublets. Dots indicate threshold determined by the true number of doublets. b Running time of the different methods (DoubletFinder failed on one of the datasets). c Rate of misclassification of the cells identified by scDblFinder as doublets (DBL) or singlets (SNG), across a large range of clustering analysis. Even in datasets which should not have neotypic doublets, the cells identified as such tend to be misclassified