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Fig. 2 | Genome Biology

Fig. 2

From: sn-spMF: matrix factorization informs tissue-specific genetic regulation of gene expression

Fig. 2

Assignment of eQTLs to factors. Effect sizes and 95% confidence intervals of four eQTLs across 49 tissues are illustrated. The fitted linear combination of factors for the eQTL is displayed in gray scale at the right of each panel. Faded colors indicate factors with coefficients with FDR ≥ 0.05. Asterisk on the tissue indicates that this eQTL was significant with FDR < 0.05 in that tissue. a A liver-specific eQTL (GLT1D1-rs1012994). b An eQTL (AATF-rs76014915) with activity in brain tissues and tibial nerve. c A ubiquitous eQTL (U2AF1-rs234719). d An eQTL (CD14-rs2563249) with ubiquitous and testis-specific effects

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