Table 1 Average estimates of \(\hat {\pi }\)

From: Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits

Scenario	Method	π_k(%)
		q_k = (0 0 0)	(1 0 0)	(0 1 0)	(0 0 1)	(1 1 0)	(1 0 1)	(0 1 1)	(1 1 1)
1a		Independent
	True	99.720	0.070	0.070	0.070	0.020	0.020	0.020	0.010
	Primo(t)	99.712	0.074	0.074	0.074	0.019	0.019	0.019	0.010
	Primo(P)	99.749	0.065	0.065	0.065	0.016	0.016	0.016	0.007
		Correlated
	True	99.720	0.070	0.070	0.070	0.020	0.020	0.020	0.010
	Primo(t)	99.712	0.073	0.073	0.073	0.019	0.019	0.019	0.011
	Primo(P)	99.749	0.065	0.065	0.065	0.016	0.016	0.016	0.007
1b		Independent
	True	99.839	0.070	0.070	0.0007	0.020	0.0002	0.0002	0.0001
	Primo(t)	99.832	0.073	0.073	0.0031	0.019	0.0002	0.0002	0.0001
	Primo(P)	99.857	0.063	0.063	0.0014	0.016	0.0002	0.0001	0.0001
		Correlated
	True	99.839	0.070	0.070	0.0007	0.020	0.0002	0.0002	0.0001
	Primo(t)	99.832	0.073	0.072	0.0029	0.019	0.0002	0.0002	0.0001
	Primo(P)	99.857	0.063	0.063	0.0013	0.016	0.0002	0.0002	0.0001

Scenario 1a simulates sparse associations for J=3 traits. Scenario 1b simulates even sparser associations for the third trait

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