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Table 1 Type I error rate of PSCAN gene-level association test and signal region detection

From: PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection

  α PSCAN-M PSCAN-V
Gene-level association test 10−4 1.0×10−4 9.5×10−5
  10−5 9.9×10−6 8.8×10−6
  2.5×10−6 2.4×10−6 2.0×10−6
Signal region detection 0.05 0.049 0.048
  0.01 0.011 0.009