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Table 1 Type I error rate of PSCAN gene-level association test and signal region detection

From: PSCAN: Spatial scan tests guided by protein structures improve complex disease gene discovery and signal variant detection

 

α

PSCAN-M

PSCAN-V

Gene-level association test

10−4

1.0×10−4

9.5×10−5

 

10−5

9.9×10−6

8.8×10−6

 

2.5×10−6

2.4×10−6

2.0×10−6

Signal region detection

0.05

0.049

0.048

 

0.01

0.011

0.009

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Genome Biology

ISSN: 1474-760X

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