Table 1 Peculiarities of scDNAseq technologies
From: Methods for copy number aberration detection from single-cell DNA-sequencing data
| Method | Uniformity | Coverage | Throughput | Suitability for CNA |
|---|---|---|---|---|
| MDA [36–38] | Low | High | Low | N |
| DOP-PCR [17–19] | High | Low | High | Y |
| MALBAC [39] | High | High | Low | Y |
| C-PCR-L [44] | High | Low | High | Y |
| SCI-seq (xSDS) [48] | Medium | Low | High | Y1 |
| DLP [40] | High | Low | High | Y |
| LIANTI [49] | High | High | Low2 | Y |
| TnBC [21] | High | Low | High | Y |
| Flow cytometry [50, 51] | High | Low | High | Y |
| 10x [43] | High | Low | High | Y |
| DLP+ [52] | High | Low | High | Y |