Skip to main content
Fig. 6 | Genome Biology

Fig. 6

From: Assessment of statistical methods from single cell, bulk RNA-seq, and metagenomics applied to microbiome data

Fig. 6

38vs38 Supragingival vs. Subgingival Plaque 16S samples a Barplot of the enrichment tests performed on the DA taxa found by each method using an adjusted p value of 0.1 as threshold for significance (top 10% ranked taxa for songbird). Each bar represents the number of findings, UP in Supragingival or DOWN in Supragingival Plaque compared to Subgingival Plaque, regarding aerobic, anaerobic, and facultative anaerobic taxa metabolism. A Fisher exact test was performed to establish the enrichment significance represented with signif. codes. b Difference between putative true positives (TP) and putative false positives (FP) (y-axis) for several significance thresholds (x-axis). Each threshold represents the top percent ranked taxa, using the ordered raw p value lists as reference (loading values for mixMC and differentials for songbird). c Aerobic metabolism taxa mutually found by 3 or more methods from the subset of the representative methods. d Anaerobic metabolism taxa mutually found by 8 or more methods from the subset of the representative methods

Back to article page