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Table 2 Ten selected PWAS-exclusive associations

From: PWAS: proteome-wide association study—linking genes and phenotypes by functional variation in proteins

Phenotype Gene symbol Chrom Generalized q value Dominant q value Dominant r/Cohen’s d Recessive q value Recessive r/Cohen’s d
HLS reticulocyte % of red cells IL6 7 1.8E−126 1 n.s. 7.3E−128 − 0.043
Hip circumference (BMI adjusted) SLC39A8 4 1.1E−23 1.6E−22 − 0.019 0.00081 − 0.0083
Eosinophil counts FOXP1 3 2.6E−16 0.89 n.s. 9.8E−17 − 0.016
Intraocular pressure FOXG1 14 2.7E−14 1 n.s. 2.6E−15 0.031
Lymphocyte counts INPP1 2 3.4E−12 0.5 n.s. 1.9E−12 − 0.014
Eosinophil counts CD80 3 3.1E−06 0.97 n.s. 1.1E−06 − 0.01
Intraocular pressure GAPT 5 4.4E−06 1 n.s. 6.5E−07 − 0.021
Red cell distribution width MLLT3 9 1.2E−05 0.76 n.s. 8.5E−06 − 0.01
Chronic lymphocytic leukemia FAM160B1 10 0.0033 0.99 n.s. 0.048 0.06
Intraocular pressure CLVS2 6 0.0043 0.98 n.s. 0.0018 0.016
  1. n.s. non-significant