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Fig. 7 | Genome Biology

Fig. 7

From: The Tug1 lncRNA locus is essential for male fertility

Fig. 7

Model of molecular modalities at Tug1 locus. Scheme showing two noncoding activities and one potential coding activity at the Tug1 locus. Tug1 locus harbors a cis-repressive element that suppresses the expression of downstream genes across multiple different tissue types. Tug1 lncRNA regulates a subset of genes in trans via an RNA-based mechanism. Lastly, the 5′ region of Tug1 harbors and evolutionary conserved ORF with a non-canonical start codon and high ribosome profiling coverage

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Genome Biology

ISSN: 1474-760X

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