Fig. 3
From: Single-cell ATAC-seq signal extraction and enhancement with SCATE
Normalization of scATAC-seq and bulk DNase-seq data. The scATAC-seq read counts versus baseline mean activities along with their Pearson correlation are shown for low-variability CREs in GM12878 (top panel) and K562 (bottom panel). Each blue dot is a low-variability CRE, defined as a CRE with almost constant activity across diverse cell types in BDDB bulk DNase-seq samples. Different plots correspond to analyses based on pooling different number of cells. In each plot, the red curve is the technical bias function fitted by SCATE