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Table 3 Sequence composition analysis for donor/acceptor duplications and pre-integration sites

From: An evolutionary driver of interspersed segmental duplications in primates

LCR16a type

Nonredundant sites

%GC (E, p value ± SE)

SINE (E, p value ± SE)

LINE (E, p value ± SE)

Donors

63

1.07, 1.6 × 10−5 ± 0.0005 *

1.47, 3.7 × 10−8 ± 2.4 × 10−5 *

1.03, 0.2 ± 0.05

Acceptors

27

1.11, 2 × 10−9 ± 6 × 10−6 *

1.68, 7.9 × 10−6 ± 0.00038 *

1.19, 0.009 ± 0.013

Pre-integration sites

13

1.18, 0.09 ± 0.08

1.66, 0.0077 ± 0.024

1.29, 0.024 ± 0.04

  1. Note: we corrected for multiple hypothesis testing using FWER for a total of nine tests. The associations that had a corrected p value + SE ≤ 0.05 are denoted with an asterisk “*” 10,000 permutations. The “E” value represents the enrichment coefficient that was calculated based on the observed value divided by the expected, where the latter was defined as the mean of 10,000 genome-wide permutations. The retrotransposon statistics refer to the enrichment in LINE and SINE counts relative to the distributed segments