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Fig. 2 | Genome Biology

Fig. 2

From: Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data

Fig. 2

Representative feature of Sierra data from a 7k cell PBMC dataset. a Counts of genes according to number of detected peaks. Dotted red line indicates median number of peaks. b Average composition of genomic feature types that peaks fall on, according to number of peaks per gene. c Percentage of cells expressing each genomic feature type with increasing stringency of cellular detection rates for peaks. d Number of genes expressing multiple (≥2) 3 UTR or exonic peaks with increasing stringency of cellular detection rates. e Comparison of PTPRC gene expression across cell populations on t-SNE coordinates with peaks identified as DU in monocytes. f, g Overlapping genes from a CD14 + monocyte vs CD4 + T cell comparisons for the PBMC 7k and PBMC 4k datasets for f DTU genes and g DE genes, visualised with [28]

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