Fig. 7
From: Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III
Pol II depletion for a long time significantly affected chromatin accessibility and Cohesin occupancy. a ChIP-Seq profiles for Cohesin (SMC1) and ATAC-Seq signals at the Dhx9 locus 1 h and 6 h after Pol II degradation are shown. The orange background regions correspond to the 4C-Seq-enriched region in Fig. 5e. b Heatmap illustrating ATAC-Seq signals centered at all promoters, enhancers, and CTCF-binding insulators (± 5 kb) before (untreated) and after auxin treatment (1 h or 6 h). These regions were ranked by their level of chromatin accessibility (from high to low) for each category in the mESCs. c Same analysis as in b but focused on Cohesin ChIP-Seq binding