Table 1 Mutations over the sexual cycle of N. crassa. Number of mutations per genome per sexual cycle were reported for each genomic region, i.e., within duplicates (defined by Dup-Blast), near duplicates (400 bp upstream and downstream flanking regions) and non-duplicates. All numbers are given as mean ± SEM. 2:2 and 3:1 refer to the pattern of segregation of mutations post meiosis
Regions | 2:2 mutations | 3:1 mutations | Total | |||
|---|---|---|---|---|---|---|
Average | Rate (× 10−8) | Average | Rate (× 10−8) | Average | Rate (× 10−8) | |
Within duplicates | 119.2 ± 20.6 | 1810 ± 313 | 0.91 ± 0.22 | 13.8 ± 3.30 | 120.1 ± 20.7 | 1820 ± 314 |
Near duplicates | 3.6 ± 0.5 | 129 ± 18 | 0.22 ± 0.08 | 7.92 ± 2.78 | 3.8 ± 0.5 | 137 ± 18.5 |
Non-duplicates | 12.5 ± 1.1 | 40.2 ± 3.48 | 0.20 ± 0.09 | 0.632 ± 0.293 | 12.7 ± 1.1 | 40.9 ± 3.52 |
All | 135.3 ± 21.4 | 334 ± 52.9 | 1.32 ± 0.30 | 3.27 ± 0.74 | 136.6 ± 21.5 | 338 ± 53.0 |