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Fig. 7 | Genome Biology

Fig. 7

From: Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping

Fig. 7

caQTL rs2692224 regulates the allele-specific response of FN1 to TGFβ signaling. HCASMC lines with different rs2692224 genotypes show distinct activation levels of a mRNA expression, b chromatin accessibility at the TSS region, and c chromosomal contacts between rs2692224 and TSS of FN1, in response to TGFβ stimulation. Shown are means ± SD; n = 3; ****P < 0.0001; ***P < 0.001; **P < 0.01; *P < 0.05

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Genome Biology

ISSN: 1474-760X

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