Fig. 6
From: Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing
Clonal evolution in response to treatment inferred from cfDNA. Plots of clonal lineages and frequency changes over time and in response to treatment for 12 patients. CNAs and mutations are labeled in the inferred lineages, as well as significant mutations identified in the resistant clones (blue, asterisk) on the right-hand side. a Patients in which subclones were identified that expanded in response to therapy. b Patients in which clonal frequencies were persistent and remained stable during treatment