Fig. 2
From: Decoding the evolutionary response to prostate cancer therapy by plasma genome sequencing
Survival analysis and correlation of cfDNA concentration with clinical features. a Kaplan-Meier overall survival plot for prostate cancer patients with total plasma DNA < 2 ng and total plasma DNA ≥ 2 ng. b Kaplan-Meier overall survival plot for patients with aneuploid and diploid cfDNA CNA profiles. c Comparison of the distribution of cfDNA concentration between accelerated and protracted progressors. d Distribution of cfDNA concentrations (ng/mL) between patients with low, intermediate, and high volume of disease. Significance for the survival analysis in a and b was calculated with the log-rank test, while the significance of the box plots in c and d was calculated using the Wilcoxon rank sum test. Red dots in c and d represent mean values