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Fig. 6 | Genome Biology

Fig. 6

From: Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Fig. 6

UCSC genome browser view of DLX5 and DLX6 and SLC25A21, MIPOL1, FOXA1, and TTC6 NCCMs clusters. For each gene, the NCCM track shows mutations, color-coded by VAF scores (electric green VAF 1–10%; fuchsia pink VAF 11–45%; blue VAF > 46%). a Variants associated with the DLX genes overlap strong methylation patterns and are found in regions of mammalian conservation. b For SLC25A21, MIPOL1, FOXA1, and TTC6, their associated NCCMs are found in regions with regulatory potential, including promoters and TFBS

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